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RT Journal Article
SR Electronic
T1 Theoretic Basis and Technical Implementations of CT Perfusion in Acute Ischemic Stroke, Part 1: Theoretic Basis
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 662
OP 668
DO 10.3174/ajnr.A1487
VO 30
IS 4
A1 Konstas, A.A.
A1 Goldmakher, G.V.
A1 Lee, T.-Y.
A1 Lev, M.H.
YR 2009
UL http://www.ajnr.org/content/30/4/662.abstract
AB SUMMARY: CT perfusion (CTP) is a functional imaging technique that provides important information about capillary-level hemodynamics of the brain parenchyma and is a natural complement to the strengths of unenhanced CT and CT angiography in the evaluation of acute stroke, vasospasm, and other neurovascular disorders. CTP is critical in determining the extent of irreversibly infarcted brain tissue (infarct “core”) and the severely ischemic but potentially salvageable tissue (“penumbra”). This is achieved by generating parametric maps of cerebral blood flow, cerebral blood volume, and mean transit time.