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PT  - JOURNAL ARTICLE
AU  - Bond, K.M.
AU  - Benson, J.C.
AU  - Cutsforth-Gregory, J.K.
AU  - Kim, D.K.
AU  - Diehn, F.E.
AU  - Carr, C.M.
TI  - Spontaneous Intracranial Hypotension: Atypical Radiologic Appearances, Imaging Mimickers, and Clinical Look-Alikes
AID  - 10.3174/ajnr.A6637
DP  - 2020 Aug 01
TA  - American Journal of Neuroradiology
PG  - 1339--1347
VI  - 41
IP  - 8
4099  - http://www.ajnr.org/content/41/8/1339.short
4100  - http://www.ajnr.org/content/41/8/1339.full
SO  - Am. J. Neuroradiol.2020 Aug 01; 41
AB  - SUMMARY: Spontaneous intracranial hypotension is a condition characterized by low CSF volume secondary to leakage through a dural defect with no identifiable cause. Patients classically present with orthostatic headaches, but this symptom is not specific to spontaneous intracranial hypotension, and initial misdiagnosis is common. The most prominent features of spontaneous intracranial hypotension on intracranial MR imaging include “brain sag” and diffuse pachymeningeal enhancement, but these characteristics can be seen in several other conditions. Understanding the clinical and imaging features of spontaneous intracranial hypotension and its mimickers will lead to more prompt and accurate diagnoses. Here we discuss conditions that mimic the radiologic and clinical presentation of spontaneous intracranial hypotension as well as other disorders that CSF leaks can imitate.IgG4immunoglobulin G4POTSpostural orthostatic tachycardia syndromeSIHspontaneous intracranial hypotensionSSsuperficial siderosis