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RT Journal Article
SR Electronic
T1 COVID-19 Neurologic Complication with CNS Vasculitis-Like Pattern
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1384
OP 1387
DO 10.3174/ajnr.A6651
VO 41
IS 8
A1 Hanafi, R.
A1 Roger, P.-A.
A1 Perin, B.
A1 Kuchcinski, G.
A1 Deleval, N.
A1 Dallery, F.
A1 Michel, D.
A1 Hacein-Bey, L.
A1 Pruvo, J.-P.
A1 Outteryck, O.
A1 Constans, J.-M.
YR 2020
UL http://www.ajnr.org/content/41/8/1384.abstract
AB SUMMARY: Coronavirus disease 2019 (COVID-19) is a viral infection caused by the Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), which spreads rapidly from person to person and manifests in most symptomatic patients as a respiratory illness, similar to prior SARS viruses. Neurologic manifestations of COVID-19 are uncommon; those so far reported include encephalopathy, stroke from large-vessel occlusion, and polyneuropathy. We report a unique neurologic complication of COVID-19 in a patient who had extensive cerebral small-vessel ischemic lesions resembling cerebral vasculitis in a characteristic combined imaging pattern of ischemia, hemorrhage, and punctuate postcontrast enhancement. Also, a characteristic lower extremity skin rash was present in our patient. Our observation lends support to the increasingly suspected mechanism of “endotheliitis” associated with this novel coronavirus.ACE2angiotensin converting enzyme 2COVID-19coronavirus disease 2019SARS-CoV-2Severe Acute Respiratory Syndrome coronavirus 2