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RT Journal Article
SR Electronic
T1 Primary Intracranial Choriocarcinoma: MR Imaging Findings
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1994
OP 1998
DO 10.3174/ajnr.A2194
VO 31
IS 10
A1 Lv, X.-F.
A1 Qiu, Y.-W.
A1 Zhang, X.-L.
A1 Han, L.-J.
A1 Qiu, S.-J.
A1 Xiong, W.
A1 Wen, G.
A1 Zhang, Y.-Z.
A1 Zhang, J.
YR 2010
UL http://www.ajnr.org/content/31/10/1994.abstract
AB SUMMARY: PICCC is the rarest, most malignant primary intracranial GCT. The purpose of this study was to describe and characterize the MR imaging findings in a series of 7 patients (6 males and 1 female; mean age, 11.9 years) with pathologically proved PICCC in our institution from 2004 to 2009. All tumors were located within the pineal (n = 6) or suprasellar (n = 1) regions. On T2-weighted MR imaging, the lesions appeared markedly heterogeneous with areas of both hypointensity and hyperintensity reflecting the histologic heterogeneity, including hemorrhage, fibrosis, cysts, or necrosis. Heterogeneous (n = 7), ringlike (n = 4), and/or intratumoral nodular (n = 3) enhancement was noted on T1-weighted images with gadolinium. These MR imaging findings, combined with patient age and serum β-HCG levels, may prove helpful in distinguishing PICCC from the more common primary brain tumors, thereby avoiding biopsy of this highly vascular tumor. GCTgerm cell tumorHCG/β-HCGhuman chorionic gonadotropin/β-human chorionic gonadotropinPICCCprimary intracranial choriocarcinoma