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RT Journal Article
SR Electronic
T1 Marchiafava-Bignami Disease with Widespread Lesions and Complete Recovery
JF American Journal of Neuroradiology
JO Am. J. Neuroradiol.
FD American Society of Neuroradiology
SP 1506
OP 1507
DO 10.3174/ajnr.A1897
VO 31
IS 8
A1 Tung, C.-S.
A1 Wu, S.-L.
A1 Tsou, J.-C.
A1 Hsu, S.-P.
A1 Kuo, H.-C.
A1 Tsui, H.-W.
YR 2010
UL http://www.ajnr.org/content/31/8/1506.abstract
AB SUMMARY: MBD is a rare disorder strongly associated with alcoholism. It is characterized pathologically by demyelination and necrosis of the corpus callosum. MBD presents with severe neurologic deficits and significant sequelae developing in most survivors. We report a patient with total clinical recovery. Serial MR imaging demonstrated typical lesions with restricted diffusion in the acute stage and total resolution without atrophy or cystic change. ADCapparent diffusion coefficientDWIdiffusion-weighted imagingMBDMarchiafava-Bignami diseaseT1WIT1-weighted imagingT2WIT2-weighted imaging