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Table 4: Diagnostic accuracy of various parameters in the differentiation between tumor recurrence and radiation necrosis for all lesions (n = 32 lesions) and for subgroup analysis of patients with DCE T1 mapping (n = 25 lesions)^{^a}
Parameters No. AUC (95% CI) P Value Optimal Threshold Sensitivity (%) Specificity (%)
ASL_CBF 32 0.81 (0.63–0.93) <.001 >30 mL/100 g/min 84 (60–97) 77 (46–95)
rCBV 32 0.70 (0.52–0.89) .033 >2.43 69 (43–87) 77 (46–95)
Corrected rCBV 32 0.71 (0.51–0.90) .037 >1.54 79 (54–94) 69 (39–91)
K^trans_SI 32 0.61 (0.41–0.82) .27 >0.0093 (min^-1) 84 (60–97) 46 (19–75)
Vp_SI 32 0.69 (0.51–0.88) .038 >0.18 79 (54–94) 62 (32–86)
K^trans_SI 25 0.66 (0.43–0.88) .17 >0.0092 (min^-1) 86 (57–98) 55 (23–83)
Vp_SI 25 0.68 (0.46–0.90) .10 >0.18 79 (49–95) 64 (31–89)
K^trans_MOLLI 25 0.59 (0.36-0.82) .44 >0.045 (min^-1) 78 (49–95) 45 (17–77)
Vp_MOLLI 25 0.80 (0.62–0.98) <.001 >0.19 86 (57–98) 63 (31–89)
K^trans_SMART 25 0.58 (0.34–0.83) .49 >0.024 (min^-1) 92 (66–1) 27 (6–61)
Vp_SMART 25 0.71 (0.49–0.88) .057 >0.12 93 (66-1) 54 (23–83)
↵a Statistics are listed with their 95% CI.