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Table 1: Patient characteristics in the derivation data and in the internal and external test data^{^a}
Characteristic Derivation Set (n = 329) Internal Test Set (n = 170) External Test Set (n = 83)
Age (yr)^{^b} 69 (59–78) 68 (59–79) 71 (63–79)
Male 173 (52.6) 89 (52.4) 43 (51.8)
Race 
 White 261 (79.3) 142 (83.5) NA
 Asian 26 (7.9) 10 (5.9)
 African American 35 (10.6) 14 (8.2)
 Other 7 (2.1) 4 (2.4)
Onset-to-CT time^{^b} 160 (82–268) 154 (79–284) 120 (89–184)
Baseline NIHSS score ^{^b} 17 (12–21) 16 (13–20) 9 (5–15)
ASPECTS^{^b} 8 (7–9) 8 (7–9) 10 (8–10)
Hypertension 222 (67.5) 127 (74.7) 49 (59.0)
Hyperlipidemia 140 (42.6) 79 (46.5) NA
Diabetes 70 (21.3) 36 (21.2) 9 (10.8)
IV alteplase 193 (58.7) 99 (58.2) 66 (79.5)
IV nerinetide 155 (47.1) 87 (51.2) 0
Occlusion site 
 ICA 71 (21.6) 39 (23.0) 8 (9.6)
 M1, MCA 248 (75.4) 125 (73.5) 26 (31.3)
 M2, MCA 10 (3.0) 6 (3.5) 10 (12.1)
 M3/M4, MCA 0 0 13 (15.7)
 ACA (A2/A3) 0 0 3 (3.6)
 PCA (P2) 0 0 2 (2.4)
 No occlusion 0 0 21 (25.3)
Note:—ACA indicates anterior cerebral artery; PCA, posterior cerebral artery; NA, not applicable.
↵a Except where indicated, data are number of patients, with percentages in parentheses.
↵b Data are the median with the IQR in parentheses.