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Table 1: Reproducibility of volume estimation of various brain structures using NeuroQuant with either a conventional or synthetic T1-weighted image stack as input^{^a}
syT1WI–T1-Weighted NQ 1.5T syT1WI–T1-Weighted NQ 3T
Mean (mL) Bias (mL) SD (mL) r Mean (mL) Bias (mL) SD (mL) r
Forebrain parenchyma 1084 −37 14 1.00 1041 −80 34 0.98
Cortical gray matter 506 8.3 14 0.98 492 −25 17 0.97
Superior lateral ventricle 29 −2.2 1.4 0.99 27 0.8 3.7 0.84
Inferior lateral ventricle 1.7 0.0 0.2 0.97 1.7 −0.1 0.3 0.78
Hippocampus 7.5 −0.8^{^b} 0.3 0.97 7.4 −0.7^{^b} 0.3 0.94
Amygdala 3.3 −0.2 0.2 0.95 3.5 −0.6^{^b} 0.2 0.84
Caudate 6.0 0.1 0.5 0.87 6.0 −0.3 0.6 0.83
Putamen 11 −2.1^{^b} 0.5 0.94 11 −2.2^{^b} 0.6 0.87
Pallidum 1.4 0.1 0.2 0.84 1.7 −0.1 0.1 0.90
Thalamus 15 −0.3 0.8 0.90 15 −2.1^{^b} 0.6 0.96
Cerebellum 145 −7.3 2.3 0.98 141 −16^{^b} 4.2 0.90
ICV 1619 −61^{^b} 17 1.00 1610 −116^{^b} 19 0.99
BPV 1273 −49^{^b} 16 1.00 1226 −103^{^b} 36 0.98
WMV 651 −50 22 0.97 622 −82 64 0.98
GMV 621 1 13 0.99 608 −62 72 0.97
CSFV 346 −13 20 0.93 384 −10 25 0.82
Note:—WMV indicates white matter volume; GMV, gray matter volume; CSFV, CSF volume.
↵a Expressed as mean volume, bias, and SD of the difference and correlation coefficient r, at 1.5T and 3T.
↵b Significant (P < .05).