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Baseline characteristics of study population
Overall IA Urokinase - IA Urokinase + P Missing (%)
No. 459 419 40 
Age (median) (IQR) (yr) 74 (63–81) 74 (63–81) 68 (60–76) .02 0
Sex male (%) 237 (51.6) 211 (50.4) 26 (65.0) .109 0
AFib = yes (%) 151 (32.9) 141 (33.7) 10 (25.0) .349 0
Hypertension = yes (%) 317 (69.1) 291 (69.5) 26 (65.0) .687 0
ODT (median) (IQR) (h) 3.03 (1.68–6.62) 3.20 (1.71–7.22) 2.42 (1.37–3.60) .021 
NIHSS on admission (median) (IQR) 12 (7–18) 13 (7–18) 11 (6–16) .07 
SBP (median) (IQR) 151 (133–171) 151 (133–172) 148 (131–161) .332 
DBP (median) (IQR) 80 (70–93) 80 (70–93) 82 (73–89) .539 
Anticoagulants prestroke = yes (%) 60 (13.1) 53 (12.6) 7 (17.5) .533 0
Antiplatelets prestroke = yes (%) 125 (27.2) 115 (27.4) 10 (25.0) .884 0
ASPECTS (median) (IQR) 8 (7–9) 8 (6–9) 9 (7–9) .032 18.5
ASITN/SIR collateral score (median) (IQR) 2 (1–3) 2 (1–3) 2 (2–3) .772 0
Note:—AFib indicates atrial fibrillation; ODT, onset-to-door time; SBP, systolic blood pressure; DBP, diastolic blood pressure; ASITN/SIR, American Society of Interventional and Therapeutic Neuroradiology/Society of Interventional Radiology.