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Table 3: Diagnostic performance of each qualitative and quantitative parameter that showed a statistically significant difference for differentiating CS from SC^a
Independent Variables Prevalence Sensitivity (%) Specificity (%) Accuracy (%) PPV (%) NPV (%) AUC (95% CI)
Lesion center (mandibular condyle) CS 7/12 SC 0/35 58.3 100.0 89.4 100.0 87.5 0.792 (0.611–0.972)
Destruction of the mandibular condyle (presence) CS 11/12 SC 20/35 91.7 42.9 55.3 35.5 93.8 0.673 (0.510–0.835)
Destruction of articular eminence/glenoid fossa (absence) CS 8/12 SC 8/35 66.7 77.1 74.5 50.0 87.1 0.719 (0.542–0.896)
Sclerosis of the articular eminence/glenoid fossa (absence) CS 10/12 SC 8/35 83.3 77.1 78.7 55.6 93.1 0.802 (0.654–0.950)
Infiltration into the tendon of the LPM (presence) CS 12/12 SC 5/35 100.0 85.7 89.4 70.6 100.0 0.929 (0.855–1.000)
Calcification (absence or stippled) CS 10/12 SC 9/35 83.3 74.3 76.6 52.6 92.9 0.729 (0.556–0.901)
Periosteal reaction (presence) CS 8/12 SC 4/35 66.7 88.6 83.0 66.7 88.6 0.776 (0.604–0.948)
Internal enhancement (presence) CS 12/12 SC 3/12 100.0 75.0 87.5 80.0 100.0 0.875 (0.719–1.000)
Mean lesion size (≥ 30.5 mm) CS 10/12 SC 5/35 83.3 85.7 85.1 66.7 93.8 0.889 (0.773–1.000)
↵a The items in parentheses correspond to the characteristics of CS, and 1 point was assigned if relevant imaging features in the parentheses were present.