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Table 1:

Basic demographics of 180 subjects with HHT and brain VMs

CharacteristicSummarya (%)
Age at enrollment (mean) (yr)34.2 (SD, 21.1)
Women111/180 (61.7%)
Curaçao criteria
    Epistaxis168/180 (93.3%)
    Mucosal telangiectasias141/180 (78.3%)
    Pulmonary AVMs91/180 (50.6%)
    Liver VMs14/180 (7.8%)
    Gastrointestinal bleeding9/180 (5.0%)
    Affected first-degree relative135/180 (75%)
Genetic mutation
    ENG109/131 (83.2%)
    ACVRL121/131 (16.0%)
    SMAD41/131 (0.7%)
DSA116/180 (64.4%)
MRA114/180 (63.3%)
CTA5/180 (2.8%)
AVM113/180 (62.8%)
AVF16/180 (8.9%)
IAs9/180 (5%)
  • a Summary is the number of observations with each value over the total available numbers (and the percentage) or the mean (SD) for continuous variables.