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Table 1: Clinical characteristics of 50 patients with PXE and 40 controls^a
Characteristics PXE (n = 50) Controls (n = 40) P Value
Clinical 
 Age (yr) 57 (SD, 12) 58 (SD, 11) .49
 Male sex (No.) 24 (48) 20 (50) .85
 BMI (kg/m²) 26 (SD, 4) 26 (SD, 4) .74
 Current smokers (No.) 6 (12) 5 (13) .86
 Systolic blood pressure (mm Hg) 136 (SD, 21) 133 (SD, 15) .49
 Diastolic blood pressure (mm Hg) 77 (SD, 12) 79 (SD, 10) .41
 Hypertension (No.) 22 (44) 18 (45) .92
 Hypercholesterolemia (No.) 43 (86) 37 (93) .33
Medication 
 Glucose-lowering medication (No.) 1 (2) 0 (0) .38
 Antihypertensive medication (No.) 13 (26) 7 (18) .40
 Cholesterol-lowering medication (No.) 26 (52) 5 (13) <.01
Laboratory 
 Calcium (mmol/L) 2.38 (SD, 0.09) 2.39 (SD, 0.09) .61
 Phosphate (mmol/L) 1.02 (SD, 0.16) 0.98 (SD, 0.16) .25
 Estimated glomerular filtration rate (mL/min/1.73m²) 90 (82–90) 88 (75–90) .17
 LDL-cholesterol (mmol/L) 2.8 (SD, 0.9) 3.6 (SD, 0.8) <.01
 25-OH vitamin D (nmol/L) 74 (SD, 36) 61 (SD, 20) .04
Note:—BMI indicates body mass index; 25-OH vitamin D = 25-hydroxy vitamin D.
^aData are presented as mean (SD), median (interquartile range), or No. (%) when appropriate. Data were analyzed using the Student t test, Mann Whitney U test, or χ² test when appropriate. A P value < .05 was statistically significant.