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Table 4: 
Associations of pulsatility with brain MR imaging findingsa
Pulsatility in PXE
Age and Sex-Adjusted (n = 50)Multivariable-Adjusted (n = 50)
MR imaging volumes (β [95% CI])
 GM (mL)3.8 [–73.9–81.6]7.4 [–71.4–86.1]
 WM (mL)22.7 [–55.8–101.3]23.1 [–57.0–103.2]
 CSF (mL)68.6 [–115.5–252.7]45.6 [–131.8–223.0]
Cortical thickness (µm)29.5 [–145.0–204.1]31.9 [–146.0–209.7]
 WML (mL)26.5 [11.6–41.3]c25.9 [10.8–40.9]c
Brain infarctions (RR [95%CI])
 Lacunar infarctions1.7 [0.1–23.6]1.8 [0.1–25.0]
 All infarctions2.3 [0.2–1.2]2.5 [0.2–33.6]
  • a For pulsatility, MR imaging volumes and infarctions are adjusted for age and sex (model 1) and age, sex, and hypertension (model 2). P < .05 was statistically significant.
  • b P < .05.
  • c P < .01.