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Table 2: Imaging findings in patients with PXE compared with controls^{^a}
Patients with PXE (n = 50) Controls (n = 40) P Value
Carotid siphon 
 Calcification mass score 17 (7–51) – –
 PI 1.05 (0.94–1.21) 0.94 (0.82–1.04) .02^{^b}
Brain MR imaging markers 
 GM (mL) 597 (SD, 53) 632 (SD, 53) <.01^{^c}
 WM (mL) 492 (SD, 52) 509 (SD, 56) .15
 CSF (mL) 337 (SD, 104) 311 (SD, 82) .18
 Cortical thickness (mm) 2.6 (SD, 0.1) 2.6 (SD, 0.1) .16
 WML (mL) 2.6 (0.5–7.5) 1.1 (0.5–2.4) .05^{^b}
Infarctions 
 Lacunar infarctions 
  No. of patients 16 (32) 6 (15) .06
  No. of infarctions 64 8 .04^{^b}
All infarctions 
  No. of patients 19 (38) 7 (18) .03^{^b}
  No. of infarctions 75 14 .02^{^b}
Note:—The en dash indicates that data on calcification mass are not available for controls.
↵a Data are presented as mean (SD), median (interquartile range), or No. (%) when appropriate. Data were analyzed using the Student t test, Mann-Whitney U test, or χ² test when appropriate. All infarctions include lacunar infarctions, 3 subcortical and 8 cortical infarctions in patients with PXE, and 6 cortical infarctions in controls. P < .05 was statistically significant.
↵b P < .05.
↵c P < .01.