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Table 3: Univariate and multivariate logistic regression analyses of LFI and 3 LFI-combined models of factors associated with rupture in AVMs
Univariable Analysis Angioarchitecture Model Hemodynamic Model Combined Model
OR (95% CI) P Value OR (95% CI) P Value OR (95% CI) P Value OR (95% CI) P Value
LFI 1.007 (1.003–1.010) .001^{^a} 1.004 (1.001–1.008) .02^{^a} 1.005 (1.001–1.009) .009^{^a} 1.004 (1.000–1.007) .03^{^a}
Mean nidus volume 0.979 (0.964–0.994) .007^{^a} 0.959 (0.931–0.988) .005^{^a}
Angioarchitecture 
 Feeding artery dilation 1.047 (0.443–2.472) .92 1.028 (0.429–2.461) .95
 Single feeding artery 0.783 (0.299–2.049) .62 1.112 (0.768–1.608) .57
 Deep venous drainage 2.315 (1.018–6.947) .05^{^a} 2.684 (1.132–6.361) .03^{^a}
 Diffuse nidus 2.863 (1.180–6.947) .02^{^a} 2.990 (1.114–8.022) .03^{^a}
 Flow-related aneurysm 3.417 (1.521–7.678) .003^{^a} 3.617 (1.544–8.474) .003^{^a}
Hemodynamic 
 Feeding artery 
  FWHM (sec) 1.067 (0.703–1.619) .76 0.949 (0.590–1.524) .83
  Drainage vein 
 FWHM (sec) 1.218 (0.750–1.978) .43 1.17 1 (0.695–1.974) .55
  MTT (ICA-sinus) 1.084 (0.811–1.448) .59 1.297 (0.933–1.803) .12
  TRV 0.999 (0.997–1.001) .26 1.004 (0.999–1.009) .14
↵a Statistical significance (P < .05).

	Univariable Analysis		Angioarchitecture Model		Hemodynamic Model		Combined Model
	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value	OR (95% CI)	P Value
LFI	1.007 (1.003–1.010)	.001^{^a}	1.004 (1.001–1.008)	.02^{^a}	1.005 (1.001–1.009)	.009^{^a}	1.004 (1.000–1.007)	.03^{^a}
Mean nidus volume			0.979 (0.964–0.994)	.007^{^a}			0.959 (0.931–0.988)	.005^{^a}
Angioarchitecture
Feeding artery dilation			1.047 (0.443–2.472)	.92			1.028 (0.429–2.461)	.95
Single feeding artery			0.783 (0.299–2.049)	.62			1.112 (0.768–1.608)	.57
Deep venous drainage			2.315 (1.018–6.947)	.05^{^a}			2.684 (1.132–6.361)	.03^{^a}
Diffuse nidus			2.863 (1.180–6.947)	.02^{^a}			2.990 (1.114–8.022)	.03^{^a}
Flow-related aneurysm			3.417 (1.521–7.678)	.003^{^a}			3.617 (1.544–8.474)	.003^{^a}
Hemodynamic
Feeding artery
FWHM (sec)					1.067 (0.703–1.619)	.76	0.949 (0.590–1.524)	.83
Drainage vein
FWHM (sec)					1.218 (0.750–1.978)	.43	1.17 1 (0.695–1.974)	.55
MTT (ICA-sinus)					1.084 (0.811–1.448)	.59	1.297 (0.933–1.803)	.12
TRV					0.999 (0.997–1.001)	.26	1.004 (0.999–1.009)	.14