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Table 3: Inter- and intraobserver agreement for a WBCE-3D TSE T1WI and OCE-2D coronal T1WI when detecting optic nerve or optic chiasm enhancement
Interobserver Intraobserver
OCE-2D T1WI κ (95% CI) WBCE-3D T1WI κ (95% CI) OCE-2D T1WI κ (95% CI) WBCE-3D T1WI κ (95% CI)
Optic nerve enhancement 0.80 (0.75–0.85) 0.65 (0.60–0.71) 0.75 (0.70–0.80) 1 (1–1)
Localization of the enhancement 
 Bilateral 0.90 (0.78–1) 0.53 (0.34–0.71) 0.75 (0.58–0.92) 1 (1–1)
 Intraorbital segment 0.76 (0.70–0.82) 0.63 (0.57–0.70) 0.81 (0.76–0.87) 0.81 (0.76–0.87)
 Canalicular segment 0.64 (0.56–0.73) 0.72 (0.65–0.79) 0.71 (0.64–0.79) 0.68 (0.58–0.75)
 Cisternal segment 0.58 (0.45–0.72) 0.54 (0.37–0.72) 0.49 (0.34–0.65) 0.81 (0.76–0.87)
 Optic chiasm 0.44 (0.15–0.73) 0.73 (0.51–0.96) 0.33 (0.04–0.61) 1 (1–1)

	Interobserver		Intraobserver
	OCE-2D T1WI κ (95% CI)	WBCE-3D T1WI κ (95% CI)	OCE-2D T1WI κ (95% CI)	WBCE-3D T1WI κ (95% CI)
Optic nerve enhancement	0.80 (0.75–0.85)	0.65 (0.60–0.71)	0.75 (0.70–0.80)	1 (1–1)
Localization of the enhancement
Bilateral	0.90 (0.78–1)	0.53 (0.34–0.71)	0.75 (0.58–0.92)	1 (1–1)
Intraorbital segment	0.76 (0.70–0.82)	0.63 (0.57–0.70)	0.81 (0.76–0.87)	0.81 (0.76–0.87)
Canalicular segment	0.64 (0.56–0.73)	0.72 (0.65–0.79)	0.71 (0.64–0.79)	0.68 (0.58–0.75)
Cisternal segment	0.58 (0.45–0.72)	0.54 (0.37–0.72)	0.49 (0.34–0.65)	0.81 (0.76–0.87)
Optic chiasm	0.44 (0.15–0.73)	0.73 (0.51–0.96)	0.33 (0.04–0.61)	1 (1–1)