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Table 2: Mean group differences, 95% CIs, and P values for residualized volumes
Difference (AD-CN) Lower 95% CN Upper 95% CN P Value
AD vs CN 
 Whole brain −73.4 −150.2 3.4 .06
 Hippocampus −1.8 −2.8 −0.8 <.001
 Frontal −1.8 −20.6 17.0 NS
 Parietal −6.1 −18.5 6.3 NS
 Temporal −10.5 −23.5 2.5 NS
 Occipital −2.6 −8.1 2.8 NS
FTD vs CN 
 Whole brain −66.4 −148.5 15.8 NS
 Hippocampus −1.2 −2.2 −0.1 0.02
 Frontal −9.5 −29.6 10.6 NS
 Parietal −0.4 −13.6 12.9 NS
 Temporal −6.5 −20.4 7.4 NS
 Occipital 0.0 −5.9 5.8 NS
FTD vs AD 
 Whole brain 7.0 −74.3 88.3 NS
 Hippocampus 0.6 −0.4 1.6 NS
 Frontal −7.7 −27.6 12.2 NS
 Parietal 5.7 −7.4 18.8 NS
 Temporal 4.0 −9.7 17.8 NS
 Occipital 2.6 −3.2 8.3 NS
Note:—NS indicates not significant.

	Difference (AD-CN)	Lower 95% CN	Upper 95% CN	P Value
AD vs CN
Whole brain	−73.4	−150.2	3.4	.06
Hippocampus	−1.8	−2.8	−0.8	<.001
Frontal	−1.8	−20.6	17.0	NS
Parietal	−6.1	−18.5	6.3	NS
Temporal	−10.5	−23.5	2.5	NS
Occipital	−2.6	−8.1	2.8	NS
FTD vs CN
Whole brain	−66.4	−148.5	15.8	NS
Hippocampus	−1.2	−2.2	−0.1	0.02
Frontal	−9.5	−29.6	10.6	NS
Parietal	−0.4	−13.6	12.9	NS
Temporal	−6.5	−20.4	7.4	NS
Occipital	0.0	−5.9	5.8	NS
FTD vs AD
Whole brain	7.0	−74.3	88.3	NS
Hippocampus	0.6	−0.4	1.6	NS
Frontal	−7.7	−27.6	12.2	NS
Parietal	5.7	−7.4	18.8	NS
Temporal	4.0	−9.7	17.8	NS
Occipital	2.6	−3.2	8.3	NS