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TABLE 2: Cox model applied to assess the effect of 1D measured tumor size on survival
Covariate Univariate Analysis Multivariate Analysis
Coefficient (b_i) HR [exp(b_i)] 95% CI P-value Coefficient (b_i) HR [exp(b_i)] 95% CI P-value
Age 0.036 1.039 (1.014–1.064) .002 0.036 1.037 (1.013–1.062) .002
Sex .015 .045
    Female (0.00) (1.00) (0.00) (1.00) 
    Male 0.725 2.070 (1.153–3.715) 0.625 1.868 (1.015–3.436) 
Previous .096 .545
Chemotherapy 
    No (0.00) (1.00) (0.00) (1.00) 
    Yes 0.433 1.542 (0.926–2.566) 0.164 1.178 (0.684–2.000) 
1D Size 0.067 1.069 (0.997–1.147) .062 0.052 1.053 (0.182–1.129) .146
HR = hazard ratio, CI = confidence interval

Covariate	Univariate Analysis				Multivariate Analysis
Covariate	Coefficient (b_i)	HR [exp(b_i)]	95% CI	P-value	Coefficient (b_i)	HR [exp(b_i)]	95% CI	P-value
Age	0.036	1.039	(1.014–1.064)	.002	0.036	1.037	(1.013–1.062)	.002
Sex				.015				.045
Female	(0.00)	(1.00)			(0.00)	(1.00)
Male	0.725	2.070	(1.153–3.715)		0.625	1.868	(1.015–3.436)
Previous				.096				.545
Chemotherapy
No	(0.00)	(1.00)			(0.00)	(1.00)
Yes	0.433	1.542	(0.926–2.566)		0.164	1.178	(0.684–2.000)
1D Size	0.067	1.069	(0.997–1.147)	.062	0.052	1.053	(0.182–1.129)	.146