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TABLE 1: Occlusion types, therapy, recanalization and lesion volumes L0-LG7
Occlusion n rt-PA Recanalization Day 7 L0 LG1 LG7 ST7
ICA/MCA 1 1 0 18.2 28.7 33.5 197.5
Carotid T 5 5 3 16.3 36.8 34.8 150.9
0.6–80.3 11.7–128.4 10.1–71.6 68.3–177.0
M1/2 7 4 5 18.0 17.9 4.4 166.3
7.0–78.8 1.7–44.1 0.2–16.2 94.8–180.6
MCA-branch 6 3 5 30.1 9.7 1.0 41.7
0.1–70.9 0.3–30.2 0.6–2.6 11.1–97.0
Note.—ICA/MCA indicates occlusion of the internal carotid artery with accompanying occlusion of the middle cerebral artery; CTO, occlusion of the intracranial ICA bifurcation (carotid T occlusion), MCA occlusion of the trunk or trifurcation (M1/2), and MCA branch occlusion (segments M3 and M4); rt-PA, recombinant tissue plasminogen activator; L0, lesion at day 0 defined by a reduced apparent diffusion coefficient (ADC); LG1 and LG7, lesion growth on T2-weighted images until day 1 and 7; and ST7 = surviving tissue at day 7 (tissue with initially reduced cerebral blood flow but without T2 prolongation at day 7). Volumes are median and range (min–max).