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TABLE 2: Mean initial perfusion values at day 0
L0 LG1 LG7 ST7
rCBF 0.32 ± 0.13 0.45 ± 0.11 0.59 ± 0.25 0.62 ± 0.10
rCBV 0.57 ± 0.18 0.71 ± 0.13 0.89 ± 0.21 1.02* ± 0.12
rMTT 1.83 ± 0.48 1.74 ± 0.39 1.57 ± 0.36 1.51 ± 0.28
rTTP 1.44 ± 0.25 1.28 ± 0.17 1.17 ± 0.14 1.13 ± 0.08
MTT [s] 8.1 ± 4.8 7.4 ± 3.6 5.8 ± 3.5 5.1 ± 2.6
TTP [s] 9.1 ± 4.1 5.8 ± 3.0 3.6 ± 2.9 2.7 ± 1.6
Note.—Mean perfusion values determined on MRI at day 0 by definition of L0, LG1, LG7 and ST7. L0 is the region with decreased ADC at day 0. LG1 and LG7 were defined by surrounding the T2 lesion on follow-up imaging at day 1 and 7, respectively. ST7 is surviving tissue with reduced cerebral blood flow at day 0 but without T2 prolongation at day 7. Transfer of LG1, LG7 and ST7 onto the initial day 0 PWI images revealed the perfusion values in these ROIs at day 0. rCBF indicates relative cerebral blood flow (relation of affected/unaffected contralateral control region); rCBV, relative cerebral blood volume; rMTT, relative mean transit time; and rTTP, relative time to peak. MTT and TTP are absolute values of bolus passage delay. P = .02.