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TABLE 6: Diagnostic performance of CT angiography in the assessment of carotid artery stenosis on the symptomatic side compared with DSA
Analysis Method of CT Angiography Sensitivity (%) Specificity (%) Overall Accuracy (%) PPV (%) NPV (%) Visual 100 (21/21) 50 (7/14) 80 (28/35) 75 (21/28) 100 (7/7) Combined MPR* 95 (20/21) 86 (12/14) 91 (32/35) 91 (20/22) 92 (12/13) Visual-quantitative† 95 (20/21) 93 (13/14) 94 (33/35) 95 (20/21) 93 (13/14)
Note.—PPV indicates positive predictive value; NPV, negative predictive value. Numbers in parentheses are number of arteries. A 50% stenosis was the cutoff point for a hemodynamically significant stenosis.
* Combined MPR was considered to be positive when either of the MPR (cross-sectional or oblique sagittal) measurements yielded a positive result.
† Visual-quantitative analysis consisted of first-line visual CT angiography interpretation and subsequent measurement only for the positive cases.