TABLE 1:

Mean and standard deviation of each perfusion measure in lesions and normal-appearing white matter in patients with multiple sclerosis compared with those of normal white matter in control subjects

Lesion/Region	Cerebral Blood Flow	Cerebral Blood Volume	Mean Transit Time
Enhancing	21.5 ± 5.1	1.4 ± 0.3	5.0 ± 1.4^¶
Nonenhancing: class 1	10.2 ± 1.8^¶	0.8 ± 0.2^£	6.3 ± 1.2^¶
Nonenhancing: class 2	20.9 ± 5.8	1.6 ± 0.5^£	4.8 ± 0.7^¶
NAWM: contralateral to enhancing	16.9 ± 3.7^§	1.06 ± 0.3	5.0 ± 1.5^¶
NAWM: contralateral to class 1	16.1 ± 5.9^§	1.09 ± 0.3	5.1 ± 1.0^¶
NAWM: contralateral to class 2	18.3 ± 6.9^§	1.24 ± 0.3	4.6 ± 0.9^¶
Normal white matter (control group)	28.3 ± 10.3	1.2 ± 0.5	1.3 ± 0.5

Enhancing indicates enhancing lesions; nonenhancing: class 1, nonenhancing lesions with decreased perfusion and perfusion measures dissimilar to those of enhancing lesions; nonenhancing: class 2, nonenhancing lesions with increased perfusion and perfusion measures similar to those of enhancing lesions; NAWM, normal appearing white matter. The Dunnett-Hsu corrected significance levels for the comparison of each lesion type and normal-appearing white matter to control normal white matter with respect to each perfusion measure are also reported here, and values of significance at the familywise levels are highlighted as
¶ : P < .001,
§ : P ≤ .01,
£ : P < .05.