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Summary of serial changes in leptomeningeal and CSF enhancement on postcontrast MR images
Patient No./Age (y)/SexFAP typeImmediately after CE3 h after CE6 h after CE24 h after CE
T1WIFLAIRT1WIFLAIRT1WIFLAIRT1WIFLAIR
1/46/FTyr114Cys±++++++++−+
2*/40/MTyr114Cys±++++++++−+
3*/52/FTyr114Cys±++++++++−+
4/31/MVal30Met−−−−−−−−
5/40/FVal30Met−−−−−−−−
6/29/FVal30Met−−−−−−−−
  • Note.—FAP indicates familial amyloid polineuropathy
  • * liver transplantation; CE, contrast enhancement; T1WI, T1-weighted imaging; FLAIR, fluid-attenuated inversion recovery imaging; ++, marked enhancement; +, mild enhancement; ±, equivocal enhancement; −, no enhancement.