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Patients with pathologic MR imaging in acute nonalcoholic Wernicke’s encephalopathy
Patient No./Sex/Age (y) Duration^* (d) Conscious State^{^†} Duration of Thiamine Therapy and Follow-ups Initial MR Imaging
1/M/56 7 Deep coma 15 d (died) T2W and FLAIR increased signals symmetrically in periaqueductal area, floor of fourth ventricle, periventricle region of third ventricle, medial thalami, capita of caudate nuclei, and frontal and parietal cortices
2/M/27 5 Mild coma 2 y T2W and FLAIR increased signals symmetrically in periaqueductal area, floor of fourth ventricle, periventricle region of third ventricle, medial thalami, and capita of caudate nuclei (Fig 4)
3/F/47 10 Deep coma 2 y T2W and FLAIR increased signals symmetrically in periaqueductal area, floor of fourth ventricle, periventricle region of third ventricle, medial thalami, capita of caudate nuclei, frontal and parietal cortices (Fig 3)
4/M/16 3 Drowsiness 1 y T2W and FLAIR increased signals in periaqueductal area
5/F/19 5 Drowsiness 1 y T2W and FLAIR increased signals in periaqueductal area (Fig 1)
6/F/26 5 Mild coma 1 y T2W and FLAIR increased signals symmetrically in periaqueductal area, floor of fourth ventricle, periventricle region of third ventricle, medial thalami, and capita of caudate nuclei (Fig 2)
Note.—FLAIR indicates fluid-attenuated inversion recovery.
* From initial neurologic presentation to initial MR imaging.
† At initial MR imaging.