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TABLE 3: Hazard ratios and confidence intervals by attribute
Attribute Grade III Gliomas Glioblastomas
HR 95% CI P Value HR 95% CI P Value
Clinical 
    Age 3.74 1.09–12.9 .036 2.29 1.35–3.86 .002
    KPS 0.96 0.93–0.99 .006 0.98 0.96–0.99 .005
    Oligodendroglioma component 1.06 0.55–2.07 .854 0.58 0.34–0.99 .047
    Resection 1.22 0.67–2.23 .517 1.08 0.85–1.37 .530
Imaging 
    Enhancing rim 1.68 0.34–8.37 .519 1.16 0.73–1.84 .522
    SE 0.79 0.38–1.61 .508 1.04 0.66–1.63 .863
    CE 3.30 0.71–15.3 .127 1.53 0.21–11.1 0.68
    ECM 2.45 0.76–7.87 .134 1.33 0.81–2.21 .264
    TCM 2.45 0.76–7.87 .134 1.31 0.72–2.36 .374
    Location 0.97 0.63–1.52 .914 1.04 0.88–1.23 .639
    Multifocal 18.7 3.06–115 .002 4.34 2.11–8.92 .001
    Necrosis 4.43 1.35–14.6 .014 1.24 0.30–5.09 .764
    nCET 0.05 0.01–0.55 .014 0.55 0.33–0.92 .023
    EM 0.32 0.07–1.35 .121 0.64 0.37–1.12 .120
    NEM 2.95 0.85–10.3 .089
    Satellites 5.18 1.11–24.1 .036 1.74 1.03–2.93 .038
    Side 0.80 0.17–3.79 .782 1.29 0.79–2.07 .300
    Size 1.16 0.90–1.50 .235 1.05 0.94–1.17 .393
    Cyst 0.03 0.00–20.8 .302 0.92 0.46–1.80 .799
    Edema 1.99 0.79–3.99 .158 1.62 1.18–2.22 .003
Note.—HR indicates hazard ratio (of dying); KPS, Karnofsky performance status; SE, solid enhancement; CE, contrast enhancement; ECM, edema crosses midline; TCM, tumor crosses midline; nCET, noncontrast-enhancing tumor; EM, enhancing margin; NEM, nonenhancing margin.