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TABLE 2: Parameter values and results of univariate analyses with age as a covariate
Controls CS− CS+ P Value
CSF % 14.3 ± 1.4 15.0 ± 2.4 16.7 ± 2.1 .319
Lesion % 0.06 ± 0.17 0.18 ± 0.51 0.34 ± 0.41 .767
MTR PH 121 ± 7.8 114 ± 10.2 112 ± 8.9 .152
MTR mean 34.1 ± 0.48 33.8 ± 0.43 33.5 ± 0.60 .147
ADC PH 3.10 ± 0.19 2.99 ± 0.19 3.07 ± 0.46 .477
ADC mean 797 ± 20 795 ± 20 798 ± 22 .627
NAA/Cre 2.20 ± 0.19 2.08 ± 0.20 1.94 ± 0.16 .064
Cho/Cre 1.01 ± 0.14 0.87 ± 0.18 0.87 ± 0.18 .055
Note.—CS indicates corticosteroids; CSF %, cerebrospinal fluid volume as a fraction of intracranial volume; Lesion %, lesion volume as a fraction of brain parenchyma volume; MTR PH and MTR mean, magnetization transfer ratio histogram peak height (arbitrary unit) and mean (percent unit); ADC PH and ADC mean, apparent diffusion coefficient histogram peak height (arbitrary unit) and mean (10⁻⁶ s/mm²); NAA/Cre and Cho/Cre, ratio of N-acetylaspartate and choline to creatine.