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TABLE 3: Pearson correlation coefficients between imaging and clinical parameters
Disease Duration CS Duration CS Dose (Daily) CS Dose (Lifetime)
Corr. P Value Corr. P Value Corr. P Value Corr. P Value
CSF % 0.129 .522 0.087 .777 −0.269 .374 0.013 .966
Lesion % 0.024 .906 −0.303 .314 0.132 .668 −0.285 .345
MTR PH −0.198 .322 0.136 .657 0.199 .515 0.201 .510
MTR mean 0.043 .831 0.135 .660 0.081 .793 0.171 .577
ADC PH −0.015 .940 0.440 .133 0.508 .076 0.503 .080
ADC mean 0.170 .397 −0.138 .654 −0.099 .747 −0.183 .550
NAA/Cre 0.122 .571 0.408 .188 0.125 .699 0.405 .192
Cho/Cre 0.326 .119 0.511 .089 0.194 .547 0.493 .103
Note.—CS indicates corticosteroids; Corr., Pearson correlation coefficient; CSF %, cerebrospinal fluid volume as a fraction of intracranial volume; Lesion %, lesion volume as a fraction of brain parenchyma volume; MTR PH and MTR mean, magnetization transfer ratio histogram peak height (arbitrary unit) and mean (percent unit); ADC PH and ADC mean, apparent diffusion coefficient histogram peak height (arbitrary unit) and mean (10⁻⁶ s/mm²); NAA/Cre and Cho/Cre, ratio of N-acetylaspartate and choline to creatine.