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Table 2: Analysis of the lesion load measurement and relative comparisons of the DIR versus the FLAIR and T2-weighted TSE sequences
Region DIR^* FLAIR^* T2TSE^* Relative Comparison (%)^†
DIR/FLAIR P Value^‡ DIR/T2 TSE P Value^‡
Infratentorial 39 25 27 56 0.02 44 0.02
Periventricular 85 81 76 5 0.16 12 0.03
Juxtacortical 54 57 49 −6 0.08 10 0.18
Mixed WM-GM 21 18 14 17 0.32 50 0.06
Deep WM 35 36 35 −3 0.32 0 1
Total 232 216 201 7 0.04 15 0.01
Note:—GM indicates gray matter; WM, white matter; DIR, double inversion recovery; FLAIR, fluid-attenuated inversion recovery; T2 TSE, T2-weighted turbo spin-echo.
* Data are numbers of detected lesions.
† Data are relative differences in the numbers of detected lesions expressed as percentages of lesion numbers identified with DIR imaging compared with the corresponding FLAIR and T2 TSE imaging.
‡ P value was obtained from the patient-wise analysis by Wilcoxon analysis for matched pairs indicating that more or fewer patients showed higher lesion load measurement with DIR imaging in comparison with the corresponding FLAIR or T2 TSE imaging.