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Table 1: Subject characteristics stratified by age
Demographics 20–34 Years(n = 44) 35–73 Years (n = 43) P
Age (years) 25.0 ± 4.5 51.0 ± 8.8 <.001
Male gender (%) 59.0 53.5 NS
Education (years) 14.3 ± 3.5 12.9 ± 3.7 .133
Positive SPHERE (%) 25.0 9.3 NS
Alcohol consumers (%) 40.0 39.5 NS
Left handers (%) 15.9 11.6 NS
Volumetric MRI 
    Global GM 783 ± 88 713 ± 73 <.001
    Global WM 467 ± 64 465 ± 51 .967
    Global CSF 308 ± 43 326 ± 51 .051
Psychometrics 
    Attention switching (errors) 0.61 ± 0.95 1.4 ± 1.8 .004
    Executive maze (seconds) 125 ± 55 257 ± 113 <.001
    Digit span (score/14) 7.3 ± 2.2 7.2 ± 1.7 .082
    Reaction time (ms) 714 ± 206 717 ± 104 .926
    Tapping 160 ± 38 156 ± 42 .693
    Estimated IQ 104 ± 9 107 ± 7 .789
Note:—NS indicates nonsignificant; SPHERE, Somatic and Psychological Health Report; GM, gray matter; WM, white matter.