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Table 1:

Neuropsychologic findings in patients with ALS and healthy subjects

TestHealthy Subjects (9)ALS Patients (16)P
Age (years)51.8 (12.7)58.6 (10.2)NS
Education (years)10.0 (4.6)8.7 (3.1)NS
MMSE (cs)28.2 (1.6)26.6 (2.9)NS
SPMT (z)−0.5 (0.6)−0.6 (0.5)NS
BPIT 10 (z)−0.1 (1.3)0.0 (0.9)NS
BPIT 30 (z)−0.1 (0.9)−0.1 (1.1)NS
FAS (z)−0.4 (0.8)−0.6 (1.3)NS
Stroop
    Word (z)−0.5 (1.2)−2.8 (4.1)NS
    Color (z)−1.6 (2.5)−4.4 (3.8)NS
    Interference (z)−0.7 (1.6)−1.9 (2.4)NS
SDMT (z)−1.4 (0.9)−2.3 (1.1).025
  • Note:—Data are presented as mean (SD). P values were determined with the use of the Mann Whitney U test. ALS indicates amyotrophic lateral sclerosis; cs, corrected score; Z, Z-score; NS, not significant; MMSE, Mini Mental State Examination; SPMT, Spinnler Prose Memory Test; BPIT 10, Brown-Peterson Interference Test at 10 seconds; BPIT 30, Brown-Peterson Interference Test at 30 seconds; FAS, Verbal Fluency Test; Stroop, Stroop Color/Word Interference Test; SDMT, Symbol Digit Modalities Test.