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Table 2: Comparison between present and previous cohorts
Present Previous
CD decline rate^a Stable −0.031 0.02
Moderate −0.32 −0.34
Rapid −1.71 −3.39
CD group size Stable 5 (31%) 10 (20%)
Moderate 7 (44%) 27 (55%)
Rapid 4 (25%) 12 (25%)
EDSS^b Stable 2.0 (1.0–6.0) 2.0 (1.5–3.5)
Moderate 1.0 (0.0–2.5) 2.0 (0.0–6.0)
Rapid 2.5 (2.0–3.0) 2.0 (0.0–3.5)
FS decline rate^a Stable −0.057 0.02
Moderate −0.20 −0.13
Rapid −1.38 −2.24
FS group size Stable 5 (31%) 10 (20%)
Moderate 6 (38%) 32 (65%)
Rapid 5 (32%) 7 (14%)
EDSS^b Stable 2.0 (1.0–6.0) 2.0 (1.5–3.5)
Moderate 1.5 (0.0–2.5) 2.0 (0.0–6.0)
Rapid 2.5 (2.0–3.0) 2.0 (0.0–3.5)
Note:—Group rates of WBNAA decline
^a mM/year;
^b EDSS score (range). Abbreviations: CD–clinical diagnosis, EDSS–Expanded Disability Status Score, FS–first symptom.