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Table 2: Intraobserver reliability and precision of hippocampal FA and MD values (n = 20)
Mean ± SD Diff ± SD t value r r_s ICC SEM CI 95% CV R95 (%)
FA left 246 ± 26 2 ± 12 0.94 .90 .88 .95 8.4 ±16 3.5% 23 (9.4%)
FA right 229 ± 20 −1 ± 9 −0.38 .91 .89 .95 6.0 ±12 2.7% 17 (7.3%)
FA mean 237 ± 17 1 ± 8 0.51 .91 .88 .95 5.3 ±10 2.2% 15 (6.2%)
MD left 782 ± 40 −1 ± 20 0.08 .91 .94 .94 13.8 ±27 1.8% 38 (4.9%)
MD right 769 ± 25 0 ± 16 0.08 .82 .81 .90 10.9 ±21 1.4% 30 (3.9%)
MD mean 775 ± 28 0 ± 14 0.10 .88 .85 .93 9.9 ±19 1.3% 27 (3.5%)
Note.— FA indicates fractional anisotropy (×10³); MD, mean diffusivity (μm²/s); Mean, pooled mean (1st and 2nd assessment of one observer) ± pooled SD; Diff, difference of 1st–2nd assessment ± SD of difference; t value, corresponding to paired t test, all P values >0.20; r, Pearson correlation coefficient; r_s, Spearman rank correlation coefficient; ICC, intraclass correlation coefficient; SEM, standard error of measurement based on within-subject variance; CI 95%, 95% confidence interval (±1.96 × SEM); CV = √(mean of within subject variance/mean squared); R95, repeatability according to Bland and Altman20; R95 = √2 × 1.96 × SEM; %, percentage of mean = R95/mean × 100.