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Table 3: rCBV_max and rCBV_T, thresholds with respective sensitivities, specificities, and p values
rCBV_max rCBV_T
High grade if metric is ≥1.75 ≥2.15 SD ≥1.7 SD₂₅ ≥1.24 SD₅₀ ≥1.35
Sensitivity (%) 98.4 95.1 95.1 95.1 95.1
Specificity (%) 67.7 80.7 100 96.8 96.8
P value (vs rCBV_max ≥ 1.75) <.001 <.001 <.001
P value (vs rCBV_max ≥ 2.15) .002 .004 .004
Note:—rCBV indicates relative cerebral blood volume; SD₅₀, SD of the top 50%; SD₂₅, SD of the top 25%.

	rCBV_max		rCBV_T
High grade if metric is	≥1.75	≥2.15	SD ≥1.7	SD₂₅ ≥1.24	SD₅₀ ≥1.35
Sensitivity (%)	98.4	95.1	95.1	95.1	95.1
Specificity (%)	67.7	80.7	100	96.8	96.8
P value (vs rCBV_max ≥ 1.75)			<.001	<.001	<.001
P value (vs rCBV_max ≥ 2.15)			.002	.004	.004