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Table 3: 
The differentially expressed genes are grouped into their respective molecular pathways
Proteolytic enzymesApoptosis of smooth muscle cells
    α-1-Antitrypsin+Caveolin−
    Cathepsin L+Fas antigen spliced variant−
    Cellular disintegrin ADAM 6e−Fast skeletal muscle troponin C mRNA−
    Hyperoxia induced (HI) 1 gene encoding a TIMP+Galectin-3+
    Matrix metalloproteinase-2+Heat shock protein 47+
    Matrix metalloproteinase-9+Muscle α -actinin subunit, N′-terminal region−
    Matrix metalloproteinase-12+Myosin heavy chain (MHC)−
    Metallo-elastase, macrophage+Myosin light chain 2−
    Osteonectin = SPARC+PPAR γ 3+
    Tissue inhibitor of metalloproteinase-2 (TIMP-2)+p53 protein−
    Tissue inhibitor of metalloproteinase-4 (TIMP-4)+Secreted frizzled-related protein 2+
Coagulation cascadeInflammatory cell recruitment
    Coagulation factor VII−Adhesion molecule VCAM-1 (VCAM-1)+
    Factor XI−Endothelial differentiation gene 1 protein+
    Glycoprotein IIb (GPIIb)+Interferon γ−
    Glycoprotein IIIa (GPIIIa)+Interleukin-1 receptor antagonist+
    Haptoglobin mRNA+Interleukin-2−
    Heme oxygenase-1 (HO1)+Interleukin-8 receptor−
    Heme oxygenase-2−MHC class II RLA-DR-α gene+
    Platelet-derived growth factor-β+Monocyte chemoattractant protein-1 (MCP-1)+
    Thrombomodulin precursor (inhibitor of coagulation)−Neutrophil-activating peptide 78 (ENA-78)−
    Thrombospondin 2-like protein (THBS2)+Neutrophil attractant/activation protein-1 (NAP-1)−
    Tissue-type plasminogen activator mRNA+
ECM proteinsOxidative stress
    α-1 type V collagen (COL5A1)−A1 Adenosine receptor+
    α-1 type X collagen+A3 Adenosine receptor−
    α-2 type I collagen−Alcohol dehydrogenase, class I+
    α-3 type IV collagen+*Apolipoprotein B−
    Bone morphogenetic protein 2 (BMP-2)−Apolipoprotein E+
    Bone morphogenetic protein 7 (BMP-7)−Atrial natriuretic polypeptide+
    Decorin=proteoglycan−Class II alcohol dehydrogenase, isozyme 1+
    Fibroblast growth factor−Clone pApoD-L) apolipoprotein D (apoD)+
    Insulin-like growth factor 1 precursor (IGF-1)+CYP4B1 isoform−
    Osteoglycin−Endothelin-1−
    Osteopontin+Endothelin B receptor−
    Transforming growth factor-β 2−Endothelin converting enzyme (ECE1)−
    Type VIII collagen α -1 chain−Endothelin receptor type A−
Glutathione S-transferase−
Inducible nitric oxide synthase (NOS2)−
NADPH-cytochrome P450 reductase−
Neuronal nitric oxide synthase NOS1+
Protein inhibitor of neuronal nitric oxide synthase+
Vascular endothelial growth factor receptor 3+
  • Note:—+ indicates that the gene was overexpressed in the aneurysm; −, the gene was underexpressed in the aneurysm.