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Table 2: Brain volume (milliliters) differences between values at week 0 and week 12, expressed in several ways*
Structure Absolute Difference Max Volume Change Max Percent Change
Mean SD Decrease Increase Decrease Increase
Whole brain 17.9 17.7 −68.3 77.3 −5.7 6.5
L frontal GM 3.3 3.6 −6.7 19.8 −4.3 12.6
R frontal GM 3.0 2.9 −6.3 17.8 −3.9 11.1
L occipital GM 1.6 1.4 −5.2 7.4 −8.8 12.5
R occipital GM 1.4 1.6 −5.1 6.8 −8.6 11.4
L parietal GM 1.6 1.2 −5.9 4.8 −9.4 7.7
R parietal GM 1.7 1.8 −7.1 8.5 −11.1 13.3
L temporal GM 2.2 2.1 −6.0 9.4 −8.9 13.9
R temporal GM 2.4 2.3 −7.7 10.7 −11.2 15.6
L frontal WM 3.8 3.7 −9.7 21.3 −6.8 15.0
R frontal WM 3.9 3.6 −11.1 21.1 −7.8 14.8
L occipital WM 1.0 1.0 −3.4 3.6 −19.9 21.1
R occipital WM 1.0 0.8 −2.9 3.2 −16.6 18.3
L parietal WM 1.3 1.2 −7.1 3.6 −15.4 7.8
R parietal WM 1.5 1.1 −5.1 3.5 −11.1 7.6
L temporal WM 1.5 1.5 −6.5 5.7 −18.1 15.8
R temporal WM 1.6 1.4 −5.0 6.5 −13.9 18.0
L caudate 0.4 0.3 −1.2 2.1 −27.9 48.8
R caudate 0.4 0.4 −2.1 1.8 −43.8 37.5
Note:—L, left; R, right; Max, maximum; GM, gray matter; WM, white matter.
* The absolute difference is unaffected by the sign of the change from week 0 to week 12. The maximal decrease and increase from week 0 to week 12 is expressed as volume (with units of milliliters) and as percent change (with respect to baseline).