1naresh
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Metabolite Ratio Childrenwith CI(n = 12) Childrenwithout CI(n = 7) Control Group(n = 10) P WM NAA/Cr 1.94 ± 0.49 2.17 ± 0.26 2.11 ± 0.36 .450 Cho/Cr 0.94 ± 0.21 0.97 ± 0.12 0.83 ± 0.19 .301 mIns/Cr 0.57 ± 0.18 0.43 ± 0.12 0.40 ± 0.10 .032 GM NAA/Cr 2.05 ± 0.41 2.01 ± 0.50 2.12 ± 0.21 .842 Cho/Cr 0.45 ± 0.08 0.45 ± 0.07 0.48 ± 0.07 .668 mIns/Cr 0.47 ± 0.88 0.36 ± 0.11 0.45 ± 0.66 .046
Note:—CI indicates cognitive impairment; WM, white matter; NAA, N-acetylaspartate; Cr, creatine; Cho, choline; mIns, myo-inositol; GM, gray matter. Groups A and B indicate children with and without cognitive impairment, respectively.