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Table 2:

Univariate analysis of MRS findings

Metabolite RatioChildrenwith CI(n = 12)Childrenwithout CI(n = 7)Control Group(n = 10)P
WM
    NAA/Cr1.94 ± 0.492.17 ± 0.262.11 ± 0.36.450
    Cho/Cr0.94 ± 0.210.97 ± 0.120.83 ± 0.19.301
    mIns/Cr0.57 ± 0.180.43 ± 0.120.40 ± 0.10.032
GM
    NAA/Cr2.05 ± 0.412.01 ± 0.502.12 ± 0.21.842
    Cho/Cr0.45 ± 0.080.45 ± 0.070.48 ± 0.07.668
    mIns/Cr0.47 ± 0.880.36 ± 0.110.45 ± 0.66.046
  • Note:—CI indicates cognitive impairment; WM, white matter; NAA, N-acetylaspartate; Cr, creatine; Cho, choline; mIns, myo-inositol; GM, gray matter. Groups A and B indicate children with and without cognitive impairment, respectively.