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Table 2: Influence of absolute concentration corrections other than for reciprocity deviations on the relative absolute concentrations of 4 major metabolites averaged in healthy control subjects (n = 14)
Variable Cho, % Cr, % NAA, % NAA+NAAG, %
With reciprocity 100.0 100.0 100.0 100.0
Coefficient of variance 13.5 9.3 11.6 12.3
Flip angle correction 93.2 94.7 94.2 93.7
    + CSF 97.7 99.2 98.7 98.2
    + Differential T2 104.0 109.7 102.8 102.3
    + Boltzmann 108.2 114.1 107.0 106.4
Note:—The top row 100% represents the concentrations without any correction other than the reciprocity correction. Subsequent rows show the accumulated effect of additional quantification step on the concentration values. Fully corrected relative values are shown in the last row. Cho indicates choline; Cr, creatine; NAA, N-acetylaspartate; NAAG, N-acetyl aspartylglutamate.