1naresh
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Absolute Metabolite Concentration Control Subjects, mM RRMS, mM SPMS, mM NAA Mean 10.96 10.34 10.04 SE 0.19 0.19 0.29 NAAG Mean 3.73 3.59 2.69* SE 0.25 0.25 0.16 tNA Mean 14.62 13.88 12.68* SE 0.26 0.26 0.28 mIns Mean 6.18 6.35 6.45 SE 0.13 0.18 0.27
Note:—mIns indicates myo-inositol; NAA, N-acetylaspartate; NAAG, N-acetylaspartate glutamate; tNA, total N-acetyl compounds including NAA and NAAG; RRMS, relapsing remitting multiple sclerosis; SPMS, secondary-progressive multiple sclerosis; NAWM, normal-appearing white matter. The MS patients were separated into RRMS and SPMS.
* Significant difference between RRMS and SPMS, P < .05 (Mann-Whitney).