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Table 1: Clinical findings in patients with multiple sclerosis and normal MR imaging scan of the brain
Gender Age at Investigation, Years Onset Disease Duration, Years Course EDSS, Points Bouts (n) during 2 Years before MR Spectroscopy Spinal MR Imaging
F 45 Sensory bout 5 RR 1.0 0 One thoracic lesion
F 52 Optic neuritis 9 RR 1.0 0 Negative (only cervical MR imaging performed)
F 21 Sensory bout 4 RR 1.5 0 Not done
F 58 Sensory bout 5 RR 2.0 0 Negative
F 46 Sensory bout 10 RR 2.0 4 Negative
F 38 Sensory bout 6 RR 2.0 1 One cervical lesion
F 50 Optic neuritis 11 RR 2.0 4 Negative
F 59 Optic neuritis 16 RR 2.5 0 Not done
F 49 Optic neuritis 6 RR 3.0 1 Negative
F 51 Sensory bout 12 SP 3.0 0 Negative
M 36 Sensory bout 15 SP 3.0 3 Not done
M 57 Optic neuritis 10 SP 5.0 0 One unspecific thoracic lesion
F 62 Motor bout 21 SP 5.5 0 Negative
M 57 Motor bout 14 SP 6.5 0 Negative
Mean 48.6 (21–62) Mean 10.2 (4–21) Mean 2.9 (1–6.5) 
Note:—Mean values are shown as a geometric mean. F indicates female; M, male; EDSS, Expanded Disability Status Scale; RR, relapsing-remitting; SP, secondary-progressive.