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Table 1: Quantitative metabolite ratios for preterm neonates (group 1) and term infants (group 2)
NAA/Cho Cho/Cr NAA/mlns mIns/Cr Glx/Cr
Basal ganglia Group 1 1.88 ± 0.35 0.53 ± 0.06 0.60 ± 0.08 1.65 ± 0.27 1.70 ± 0.27
Group 2 2.49 ± 0.40^* 0.39 ± 0.06^** 0.94 ± 0.20^** 1.06 ± 0.22^** 2.20 ± 0.49
Thalamus Group 1 2.33 ± 0.24 0.53 ± 0.05 0.87 ± 0.09 1.43 ± 0.13 1.69 ± 0.26
Group 2 2.71 ± 0.42 0.44 ± 0.05^** 1.15 ± 0.10^** 1.03 ± 0.10^** 1.77 ± 0.10
Optic radiations Group 1 2.04 ± 0.10 0.54 ± 0.06 0.60 ± 0.13 1.96 ± 0.70 1.69 ± 0.32
Group 2 2.48 ± 0.50 0.56 ± 0.13 0.67 ± 0.17 2.14 ± 0.74 3.13 ± 2.14
Calcarine gray matter Group 1 2.28 ± 0.25 0.60 ± 0.07 0.43 ± 0.04 3.18 ± 0.35 4.02 ± 0.88
Group 2 2.87 ± 0.58 0.46 ± 0.07^** 0.47 ± 0.09 2.75 ± 0.39 3.23 ± 0.66
Posterior white matter Group 1 2.35 ± 0.42 0.56 ± 0.02 0.73 ± 0.20 1.85 ± 0.16 2.25 ± 0.33
Group 2 2.58 ± 0.50 0.53 ± 0.10 0.66 ± 0.16 2.13 ± 0.68 3.01 ± 0.70
Frontal white matter Group 1 2.04 ± 0.60 0.69 ± 0.18 0.55 ± 0.10 2.48 ± 0.55 3.38 ± 0.76
Group 2 2.46 ± 0.46 0.59 ± 0.13^* 0.76 ± 0.14^* 1.90 ± 0.31^* 3.68 ± 1.07
Note:—NAA indicates N-acetylaspartate; Cho, choline; Cr, creatine; mlns, myo-inositol; Glx, glutamate/glutamine.
* P < .05.
** P < .005.