1naresh
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No. IV tPA dose (mg/kg) IA tPA dose (mg) Total tPA Dose (mg) Total tPA dose (mg/kg) IV tPA only 17 0.68 ± 0.14 52.6 ± 17.3 0.68 ± 0.14 Lower dose 12 0.60 ± 0.04 45.0 ± 8.97 0.60 ± 0.04 Regular dose 5 0.88 ± 0.03 70.9 ± 19.5 0.88 ± 0.03 IA tPA only 27 14.0 ± 9.65 14.0 ± 9.65 0.19 ± 0.14 IA + IV tPA 13 0.67 ± 0.17 7.54 ± 3.91 69.3 ± 12.5 0.76 ± 0.17 Lower dose 7 0.53 ± 0.05 8.87 ± 4.67 64.4 ± 8.74 0.61 ± 0.04 Regular dose 6 0.85 ± 0.06 6.00 ± 2.28 74.9 ± 14.5 0.93 ± 0.08
Note:—IV indicates intravenous; IA, intraarterial; tPA, tissue plasminogen activator.
Doses are shown as means ± SD; 3 patients each received 250,000 U of urokinase IA and IV tPA (not shown).