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Table 2: Summary of apparent diffusion coefficient (ADC) values of tumors, ADC ratios of tumors to normal-appearing brain, and ADC values of normal-appearing brain parenchyma for juvenile pilocytic astrocytomas (JPA), ependymomas, and medulloblastomas
JPA Ependymoma Medulloblastoma
Tumor ADC range (1-ROI and 3-ROI) (×10⁻³ mm²/s) 1.24–2.09 0.97–1.29 0.48–0.93
Mean tumor ADC value (3-ROI) (×10⁻³ mm²/s) (±SD) 1.65 ± 0.27 1.10 ± 0.11 0.66 ± 0.15
Tumor ADC ratio range 1.62–2.99 1.15–1.85 0.66–1.10
(1-ROI and 3-ROI) 
Mean tumor ADC ratio (3-ROI) (±SD) 2.11 ± 0.36 1.39 ± 0.18 0.84 ± 0.14
Mean tumor ADC ratio (1-ROI) (±SD) 2.18 ± 0.42 1.47 ± 0.22 0.86 ± 0.15
Normal brain ADC (3-ROI) (±SD) 0.78 ± 0.07 0.79 ± 0.04 0.78 ± 0.08
Age range (Mean Age) 20 mo−21 y (8.5 y) 4 y−22 y (11 y) 6 wk–23 y (10.5 y)
Note:—1-ROI method indicates the approach wherein a single region of interest of solid enhancing tumor to normal-appearing cerebellum was performed; 3-ROI method, approach used by placing additional regions of interest in the tumor and bilateral centrum semiovale.