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Table 1: 
Quantitative 1H-MR spectroscopy at 6 years 5 months and 6 years 11 months of age
2nd MR Imaging3rd MR ImagingNormative
White matter
    NAA1.772.136.9 ± 0.6
    Cr4.814.814.9 ± 0.4
    Cho1.871.831.6 ± 0.3
Gray matter
    NAA4.735.028.3 ± 0.8
    Cr6.976.537.6 ± 0.6
    Cho1.852.461.9 ± 0.2
  • Note:—NAA indicates N-acetylaspartate; Cr, creatine; Cho, choline. Metabolite concentrations are μmol/L. NAA concentrations are significantly reduced in the white and central gray matter; Cho and Cr concentrations are normal. Normative age-matched regional values were derived from Pouwels et al.11