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Table 1: Metabolite peak-area ratios for Lac/Cr, Lac/NAA, Lac/Cho, NAA/Cr, NAA/Cho, and Cho/Cr
Metabolite Ratio Control Group (n = 10) Neonatal Encephalopathy Group (n = 17) P Values
Normal/Mild Outcome (n = 10) Severe/Fatal Outcome (n = 7) Control Versus Normal/Mild Outcome Control Versus Severe/Fatal Outcome Normal/Mild Outcome Versus Severe/Fatal Outcome
Lac/Cr 0.38 (0.10) 0.41 (0.13) 0.70 (0.45–2.65) .61 .04^* .06
Lac/NAA 0.24 (0.06) 0.29 (0.09) 0.54 (0.35–2.66) .11 .02^* .03^*
Lac/Cho 0.15 (0.03) 0.19 (0.05) 0.32 (0.22–1.26) .06 .02^* .04^*
NAA/Cr 1.59 (0.19) 1.41 (0.28) 1.16 (0.14) .09 <.001^* .04^*
NAA/Cho 0.66 (0.08) 0.67 (0.09) 0.56 (0.11) .73 .04^* .04^*
Cho/Cr 2.47 (0.57) 2.10 (0.31) 2.12 (0.36) .09 .17 .91
Note:—Lac indicates lactate; NAA, N-acetylaspartate; Cho, choline; Cr, creatine.
* Denotes statistically significant differences between the groups. Values are mean (SD) and median (interquartile range) as appropriate.