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Mean and SDs of MFC measure in different brain regions between patients with relapsing-remitting MS and control subjects*
RegionPatientsControlsP Value
Globus pallidus867.7 ± 177.0699.7 ± 145.0.007
Putamen540.0 ± 144.6387.0 ± 106.4.002
Thalamus247.2 ± 69.0189.3 ± 71.6.03
Frontal white matter94.7 ± 27.491.5 ± 41.9.81
Genu of corpus callosum190.9 ± 44.4174.1 ± 45.5.67
Splenium of corpus callosum108.3 ± 34.8103.0 ± 34.4.31
  • * Least squares regression was used to compare patients and controls with respect to the mean MFC generated from both sides of the deep gray matter and white matter regions while P values were adjusted for age and sex.