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Table 2: Diffusion tensor measurements (median [ranges]) of selected NAWM regions among AD, MCI, and NC subjects^a
AD (n = 6) MCI (n = 11) NC (n = 8)
Frontal FA 0.25 (0.22–0.29)^b 0.29 (0.25–0.38) 0.33 (0.27–0.39)
Frontal DA 1.13 (0.97–1.18) 1.06 (0.95–1.13) 1.07 (1.03–1.13)
Frontal DR 0.78 (0.67–0.85)^b^c 0.69 (0.60–0.75) 0.64 (0.59–0.74)
Temporal FA 0.38 (0.34–0.43)^b^c 0.43 (0.40–0.48)^b 0.50 (0.45–0.58)
Temporal DA 1.18 (1.16–1.24)^b 1.20 (1.15–1.36)^b 1.29 (1.27–1.36)
Temporal DR 0.66 (0.61–0.71)^b 0.61 (0.55–0.70) 0.57 (0.48–0.62)
Parietal FA 0.38 (0.35–0.43)^b 0.40 (0.33–0.43)^b 0.46 (0.44–0.48)
Parietal DA 1.14 (1.07–1.25) 1.12 (1.05–1.18) 1.15 (1.12–1.23)
Parietal DR 0.63 (0.61–0.66)^b 0.60 (0.57–0.64)^b 0.57 (0.54–0.59)
Occipital FA 0.42 (0.36–0.43) 0.45 (0.39–0.56) 0.45 (0.33–0.50)
Occipital DA 1.19 (1.15–1.24) 1.21 (1.06–1.42) 1.19 (1.09–1.38)
Occipital DR 0.62 (0.60–0.66) 0.60 (0.52–0.68) 0.59 (0.50–0.72)
Note:—NC indicates control subjects.
a DA and DR are in units of 10⁻³ mm²/s.
b Statistically significant versus NC.
c Statistically significant versus MCI.