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Table 1: 
Demographic and clinical characteristics
CharacteristicNormal Cognition (n = 43)MCI (n = 19)AD (n = 55)
Sex (M/F)a15/285/1428/27
Age (yr)73 (±7)77 (±6)74 (±8)
Education (yr)11 (±4)10 (±4)10 (±4)
MMSE28 (±2)26 (±1)18 (±5)b
WMH vol. (mL)6.4 (±8)4.7 (±8)6.5 (±9)
Atrophyc74.7 (±4)72.5 (±5)71.2 (±5)d
  • Note:—Data are represented as mean (±SD). vol. indicates volume.
  • a χ2 test.
  • b Differs from the group with normal cognition and MCI (P < .001).
  • c Atrophy is defined as total parenchyma volume divided by intracranial volume. Therefore, the numbers represent the percentage of intracranial volume occupied by brain parenchyma.
  • d Differs from the group with normal cognition (P < .01).