1naresh
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Features SCA1 (n = 14) SCA2 (n = 11) CAG repeats (range) 40–58 35–47 Age at onset (years) 40.3 ± 10 35.9 ± 10 Disease duration (years) 8.2 ± 4.9 7.4 ± 4.4 Dysarthria (%) 100 87 Nystagmus (%) 21 0 Vertical gaze palsy (%) 43 73 Horizontal gaze palsy (%) 14 33 Slow saccades (%) 36 87 Increased bicep reflexes (%) 93 20 Increased patellar reflexes (%) 100 20 Lower limb spasticity (%) 71 13 Babinski sign (%) 79 60 Decreased vibration sense (%) 83 87 Dysphagia (%) 50 80 Amyotrophy (%) 7 0 Cognitive impairment (%) 7 13 Sphincteric disturbances (%) 29 47
Note:—CAG indicates cytosine adenine guanine.