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Table 3: Sensitivity and specificity analyses using perfusion parameter thresholds
Criteria High Grade Low Grade
Sensitivity 95% CI Specificity 95% CI
nCBV >1.92 85.7% (12/14) (57.2%–98.2%) 100% (5/5) (47.8%–100%)
nCBF >1.48 71.4% (10/14) (41.9%–91.6%) 100% (5/5) (47.8%–100%)
nMTT <1.94 92.9% (13/14) (66.1%–99.8%) 40% (2/5) (5.3%–85.3%)
nCBV >1.92 or nCBF >1.48 92.9% (13/14) (66.1%–99.8%) 100% (5/5) (47.8%–100%)
Note:—CI indicates confidence interval.

Criteria	High Grade		Low Grade
Criteria	Sensitivity	95% CI	Specificity	95% CI
nCBV >1.92	85.7% (12/14)	(57.2%–98.2%)	100% (5/5)	(47.8%–100%)
nCBF >1.48	71.4% (10/14)	(41.9%–91.6%)	100% (5/5)	(47.8%–100%)
nMTT <1.94	92.9% (13/14)	(66.1%–99.8%)	40% (2/5)	(5.3%–85.3%)
nCBV >1.92 or nCBF >1.48	92.9% (13/14)	(66.1%–99.8%)	100% (5/5)	(47.8%–100%)