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Table 1: Summary of patient histories
Patient no: Age/Sex Primary Disorder Type of Transplant Interval between Transplantation and Symptoms Onset Neurological Symptoms Specimen and Quantity of HHV-6 PCR Outcome
Disorientation Short-term Memory Loss Coma Hypopnea Convulsion
1:49/F Acute leukemia Cord blood stem cell 27 + + 9000 (CSF) and 3000 (blood^*) copies/mL Improved (remaining disorientation and memory loss)
2:41/F Acute leukemia (Peripheral blood stem cell) (979) + + 49,000 copies/mL (CSF) Improved (remaining disorientation and memory loss)
3:55/M Non-Hodgkin lymphoma Bone marrow 22 + + 400,000 copies/mL (blood) Dead (sepsis)
4:52/M Non-Hodgkin lymphoma Bone marrow 14 + + + 58,000 copies/mL (CSF) Improved
5:36/M Acute leukemia Bone marrow 19 + + + + + 2300 copies/mL (CSF) Dead (intestinal pneumonitis)
6:37/F Acute leukemia Bone marrow 17 + + + 3000 copies/mL (CSF) Dead (liver failure)
Note:—HHV-6 indicates human herpesvirus 6; PCR; polymerase chain reaction.
* Peripheral blood.